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L-arginine infusion lowers blood pressure in children. J Pediatr 2001 Nov;139(5):747-9

Date

11/20/2001

Pubmed ID

11713459

DOI

10.1067/mpd.2001.118888

Scopus ID

2-s2.0-0035196654 (requires institutional sign-in at Scopus site)   7 Citations

Abstract

Eleven children were studied during L-arginine infusion. Blood pressure decreased, and mean plasma L-arginine and L-citrulline increased compared with baseline levels. The change in blood pressure was inversely related to the change in plasma L-citrulline. These results suggest that L-arginine decreased blood pressure via increased nitric oxide production.

Author List

Nelin LD, Hoffman GM

Author

George M. Hoffman MD Chief, Professor in the Anesthesiology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adolescent
Arginine
Blood Pressure
Child
Child, Preschool
Humans
Infusions, Intravenous
Nitric Oxide