Faculty Collaboration Database

Esophageal and upper esophageal sphincter motor function in babies. Am J Med 2001 Dec 03;111 Suppl 8A:64S-68S

Date

12/26/2001

Pubmed ID

11749928

DOI

10.1016/s0002-9343(01)00848-8

Scopus ID

2-s2.0-0035804024 (requires institutional sign-in at Scopus site)   35 Citations

Abstract

The incidence of concomitant feeding and airway-related disorders is high among premature infants and babies with congenital anomalies. The cause of these disorders is commonly attributed to foregut dysfunction, and the approach to diagnosis and management is largely empiric. Management strategies usually are based on the failure to improve feeding tolerance with advancing maturation and the presence of supraesophageal complications of reflux disease. Very little information exists about the functional development of deglutitive and airway-protective mechanisms in neonates. The purpose of this article is to review the available information on esophageal and upper esophageal sphincter (UES) motor function in human infants. Understanding the maturation of the motor functions of the pharynx-UES and esophagus and related airway-protection responses is essential for determining the pathophysiologic basis of feeding-related airway disorders.

Author List

Jadcherla SR, Shaker R

Author

Reza Shaker MD Assoc Provost, Sr Assoc Dean, Ctr Dir, Chief, Prof in the Medicine department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Child Development
Esophagogastric Junction
Esophagus
Female
Humans
Infant
Infant, Newborn
Infant, Premature
Male
Manometry
Pharynx
Prognosis
Risk Factors