Faculty Collaboration Database

Inflammatory myofibrohistiocytic proliferation simulating sarcoma in children. Cancer 1990 Apr 01;65(7):1626-34

Date

04/01/1990

Pubmed ID

2311072

DOI

10.1002/1097-0142(19900401)65:7<1626::aid-cncr2820650729>3.0.co;2-v

Scopus ID

2-s2.0-0025248493 (requires institutional sign-in at Scopus site)   140 Citations

Abstract

The term "inflammatory myofibrohistiocytic proliferation" (IMP) has been proposed to replace the conventional designations of plasma cell granuloma and inflammatory pseudotumor. Three cases of extrapulmonary IMP in children are reported, including an intracerebral lesion which has been formerly undescribed. In children, IMP may be associated with microcytic hypochromic anemia, hypergammaglobulinemia, and high erythrocyte sedimentation rate. In this clinical setting, differentiation of a rapidly growing but benign IMP from a bona fide sarcoma is of paramount importance.

Author List

Tang TT, Segura AD, Oechler HW, Harb JM, Adair SE, Gregg DC, Camitta BM, Franciosi RA

Authors

David C. Gregg MD Associate Professor in the Radiology department at Medical College of Wisconsin
Annette D. Segura MD Adjunct Assistant Professor in the Pathology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Abdominal Neoplasms
Adolescent
Brain Neoplasms
Child, Preschool
Collagen
Cytoplasm
Diagnosis, Differential
Female
Fibroma
Granuloma
Granuloma, Plasma Cell
Humans
Infant
Male
Sarcoma
Terminology as Topic
Thoracic Neoplasms
Tomography, X-Ray Computed