Faculty Collaboration Database

Nerve repair at different angles of attachment: experiment in rats. J Reconstr Microsurg 2002 Nov;18(8):703-8

Date

01/14/2003

Pubmed ID

12524590

DOI

10.1055/s-2002-36503

Scopus ID

2-s2.0-0036856287 (requires institutional sign-in at Scopus site)   12 Citations

Abstract

Sixteen rats underwent two procedures to test the efficacy of oblique vs. transverse nerve repair. On the left, the peroneal nerve was transected at an oblique angle (30-degree) with subsequent oblique end-to-end repair performed. On the right, the peroneal nerve was transected at a transverse angle (90-degree) with subsequent end-to-end repair. At 3.5 months postoperatively, the moist muscle weight of the extensor digitorum longus (EDL) and tetanic force were measured, and axons were counted in donor and recipient nerves. Muscle volume, tetanic force, and moist weight of EDL muscles were statistically significantly higher on the left side (oblique) than on the right (transverse). Histologic analysis with nerve axon counting of the recipient peroneal nerve revealed significantly more regenerated nerve fibers on the left than on the right. The authors concluded that oblique nerve repair enhances nerve-fiber sprouting from the proximal donor nerve by increasing the coapted surface area, thus improving muscle recovery.

Author List

Yan YH, Yan JG, Sanger JR, Zhang LL, Riley DA, Matloub HS

Authors

Hani S. Matloub MD Professor in the Plastic Surgery department at Medical College of Wisconsin
James R. Sanger MD Professor in the Plastic Surgery department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Animals
Axons
Male
Microsurgery
Muscle, Skeletal
Myocardial Contraction
Nerve Fibers
Nerve Regeneration
Peroneal Nerve
Rats
Rats, Sprague-Dawley
Recovery of Function