Faculty Collaboration Database

A perspective on the selection of unrelated donors and cord blood units for transplantation. Blood 2012 Jul 12;120(2):259-65

Date

05/19/2012

Pubmed ID

22596257

Pubmed Central ID

PMC3398760

DOI

10.1182/blood-2012-03-379032

Scopus ID

2-s2.0-84864144424 (requires institutional sign-in at Scopus site)   125 Citations

Abstract

Selection of a suitable graft for allogeneic hematopoietic stem cell transplantation involves consideration of both donor and recipient characteristics. Of primary importance is sufficient donor-recipient HLA matching to ensure engraftment and acceptable rates of GVHD. In this Perspective, the National Marrow Donor Program and the Center for International Blood and Marrow Transplant Research provide guidelines, based on large studies correlating graft characteristics with clinical transplantation outcomes, on appropriate typing strategies and matching criteria for unrelated adult donor and cord blood graft selection.

Author List

Spellman SR, Eapen M, Logan BR, Mueller C, Rubinstein P, Setterholm MI, Woolfrey AE, Horowitz MM, Confer DL, Hurley CK, National Marrow Donor Program, Center for International Blood and Marrow Transplant Research

Authors

Mary Eapen MBBS, DCh, MRCPI, MS Professor in the Medicine department at Medical College of Wisconsin
Mary M. Horowitz MD, MS Professor in the Medicine department at Medical College of Wisconsin
Brent R. Logan PhD Director, Professor in the Institute for Health and Equity department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adult
Adult Stem Cells
Cord Blood Stem Cell Transplantation
Donor Selection
Hematopoietic Stem Cell Transplantation
Histocompatibility Testing
Humans
Infant, Newborn
Peripheral Blood Stem Cell Transplantation
Tissue Donors
Transplantation Immunology
United States