Incidence and clinical characteristics of periocular infantile hemangiomas. Arch Ophthalmol 2012 Jul;130(7):889-93
Date
07/11/2012Pubmed ID
22776927Pubmed Central ID
PMC3673779DOI
10.1001/archophthalmol.2012.213Scopus ID
2-s2.0-84863794853 (requires institutional sign-in at Scopus site) 13 CitationsAbstract
OBJECTIVE: To report the incidence, demographics, and clinical findings among a population-based cohort of children with periocular infantile hemangiomas.
METHODS: The medical records of all patients (<19 years of age) diagnosed as having periocular infantile hemangiomas while residing in Olmsted County, Minnesota, from January 1, 1965, through December 31, 2004, were retrospectively reviewed.
RESULTS: Forty-three children were diagnosed as having periocular infantile hemangiomas during the 40-year period, yielding an incidence of 5.4 per 100,000 individuals younger than 19 years (95% CI, 3.8-7.1) or a birth prevalence of 1 in 1586 live births. Thirty children (70%) were female (P<.001). There was a history of maternal infertility in approximately 1 in 5 children and premature birth in 1 in 8 children. Twenty-six children (61%) had other abnormalities, including secondary hemangiomas in 9 (21%). Forty-one patients (95%) had unilateral disease, and 37 hemangiomas (86%) were located on the upper eyelid.
CONCLUSIONS: In this population-based study, periocular infantile hemangiomas occurred in 1 in 1586 live births and were most prevalent on the unilateral upper eyelid of white female patients. Prevalent associations included maternal infertility and premature birth. Other abnormalities, including secondary hemangiomas in 1 in 5 children, were common in this cohort.
Author List
Alniemi ST, Griepentrog GJ, Diehl N, Mohney BGAuthor
Gregory J. Griepentrog MD Associate Professor in the Ophthalmology and Visual Sciences department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
ChildChild, Preschool
Comorbidity
Eyelid Neoplasms
Female
Hemangioma
Humans
Incidence
Infant
Infant, Newborn
Male
Maternal Age
Minnesota
Paternal Age
Premature Birth
Prevalence
Retrospective Studies
