mRNA decay: x (XRN1) marks the spot. Mol Cell 2003 May;11(5):1126-8
Date
05/29/2003Pubmed ID
12769838DOI
10.1016/s1097-2765(03)00198-9Scopus ID
2-s2.0-0038730985 (requires institutional sign-in at Scopus site) 25 CitationsAbstract
Degradation of mRNA is a vital aspect of gene expression. In yeast, Dcp1p, Dcp2p, Lsm1-7p, and Xrn1p are required for mRNA decay and are localized within discrete cytoplasmic foci; in the May 2 issue of Science, Sheth and Parker provide compelling evidence that these foci represent sites for mRNA decay.
Author List
Long RM, McNally MTAuthor
Roy M. Long PhD Assistant Dean, Professor in the Medical School Regional Campuses department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AnimalsCytoplasm
Endoribonucleases
Eukaryotic Cells
Exoribonucleases
Humans
RNA Cap-Binding Proteins
RNA, Messenger
RNA-Binding Proteins
Saccharomyces cerevisiae Proteins
Yeasts