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mRNA decay: x (XRN1) marks the spot. Mol Cell 2003 May;11(5):1126-8

Date

05/29/2003

Pubmed ID

12769838

DOI

10.1016/s1097-2765(03)00198-9

Scopus ID

2-s2.0-0038730985   24 Citations

Abstract

Degradation of mRNA is a vital aspect of gene expression. In yeast, Dcp1p, Dcp2p, Lsm1-7p, and Xrn1p are required for mRNA decay and are localized within discrete cytoplasmic foci; in the May 2 issue of Science, Sheth and Parker provide compelling evidence that these foci represent sites for mRNA decay.

Author List

Long RM, McNally MT

Authors

Roy M. Long PhD Assistant Dean, Associate Professor in the Medical School Regional Campuses department at Medical College of Wisconsin
Mark T. McNally PhD Associate Professor in the Microbiology and Immunology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Animals
Cytoplasm
Endoribonucleases
Eukaryotic Cells
Exoribonucleases
Humans
RNA Cap-Binding Proteins
RNA, Messenger
RNA-Binding Proteins
Saccharomyces cerevisiae Proteins
Yeasts