Faculty Collaboration Database

Anatomic distribution of renal artery stenosis in children: implications for imaging. Pediatr Radiol 2006 Oct;36(10):1032-6

Date

07/05/2006

Pubmed ID

16819600

DOI

10.1007/s00247-006-0253-8

Scopus ID

2-s2.0-33748632366 (requires institutional sign-in at Scopus site)   70 Citations

Abstract

BACKGROUND: Renal artery stenosis (RAS) causes significant hypertension in children. Frequently, pediatric RAS occurs with systemic disorders. In these cases, stenoses are often complex and/or include long segments. We believed that hypertensive children without comorbid conditions had a different lesion distribution and that the difference might have implications for imaging and treatment.

OBJECTIVE: To identify locations of RAS lesions in these hypertensive children without comorbid conditions.

MATERIALS AND METHODS: Patients who had renal angiography for hypertension from 1993 to 2005 were identified. Patients with systemic disorders, renovascular surgery, or normal angiograms were excluded. The angiograms of the remaining patients were reviewed for number, type, and location of stenoses.

RESULTS: Eighty-seven patients underwent renal angiography for hypertension; 30 were excluded for comorbid conditions. Twenty-one of the remaining 57 patients had abnormal angiograms; 24 stenoses were identified in those patients. All were focal and distributed as follows: 6 (25%) main renal artery, 12 (50%) 2nd order branch, 3 (12.5%) 3rd order branch, and 3 (12.5%) accessory renal artery.

CONCLUSION: Hypertensive children without comorbid conditions who have RAS usually have single, focal branch artery stenoses. This distribution supports angiography in these patients because of its superior sensitivity in detecting branch vessel disease and its therapeutic role in percutaneous transluminal renal angioplasty.

Author List

Vo NJ, Hammelman BD, Racadio JM, Strife CF, Johnson ND, Racadio JM

Author

Nghia (Jack) Vo MD Chief, Professor in the Radiology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adolescent
Angiography
Child
Child, Preschool
Female
Humans
Hypertension, Renovascular
Infant
Male
Renal Artery Obstruction