Recent advances in systemic therapies and radiotherapy for gallbladder cancer. Surg Oncol 2013 Mar;22(1):61-7
Date
01/08/2013Pubmed ID
23290830DOI
10.1016/j.suronc.2012.12.001Scopus ID
2-s2.0-84873732296 (requires institutional sign-in at Scopus site) 32 CitationsAbstract
Adjuvant treatment is not routine following resection for gallbladder cancer as most regimens have low response rates. In the palliative setting, recent advances have been made regarding combination chemotherapies and both gemcitabine/cisplatin and gemcitabine/oxaliplatin appear to be superior to single-agent 5FU, which has very little efficacy in this disease. There are isolated reports of dramatic responses to targeted monoclonal agents. The role of radiotherapy has recently been revisited, however, its effectiveness when patients are adequately surgically treated remains to be demonstrated.
Author List
Caldow Pilgrim CH, Groeschl RT, Quebbeman EJ, Gamblin TCAuthor
Thomas Clark Gamblin MD Professor in the Surgery department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Antineoplastic Combined Chemotherapy ProtocolsChemoradiotherapy
Gallbladder Neoplasms
Humans
