Faculty Collaboration Database

Bilateral intracranial electroencephalographic monitoring immediately following corpus callosotomy. Epilepsia 2010 Oct;51(10):2203-6

Date

04/14/2010

Pubmed ID

20384766

DOI

10.1111/j.1528-1167.2010.02568.x

Scopus ID

2-s2.0-78649306915 (requires institutional sign-in at Scopus site)   11 Citations

Abstract

Although many patients with medically refractory focal epilepsy are candidates for resective surgery, patients with multifocal epilepsy and symptomatic generalized epilepsy remain difficult to treat medically and surgically. Corpus callosotomy has been utilized since 1940 for the treatment of seizures, with reports of efficacy in multiple seizure types. Previous studies have demonstrated subsequent lateralization of bilateral/bisynchronous epileptiform activity following callosotomy. To investigate the efficacy of bilateral intracranial electroencephalographic studies immediately following corpus callosotomy, we retrospectively identified 26 patients who underwent corpus callosotomy at our center, 18 of whom had intracranial monitoring following corpus callosotomy. Five of the 18 had focal resections following intracranial electroencephalography (EEG). No patients were seizure free following callosotomy or resection. No differences in postoperative outcomes were seen between patients with intracranial EEG versus those without.

Author List

Silverberg A, Parker-Menzer K, Devinsky O, Doyle W, Carlson C

Author

Chad Carlson MD Professor in the Neurology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adolescent
Corpus Callosum
Electrodes, Implanted
Electroencephalography
Epilepsy
Female
Follow-Up Studies
Functional Laterality
Humans
Male
Preoperative Care
Retrospective Studies
Treatment Outcome
Vagus Nerve Stimulation