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Immune trigeminal sensory neuropathy with esophageal achalasia: improvement with long-term immunotherapy. Muscle Nerve 2011 Feb;43(2):289-93

Date

01/22/2011

Pubmed ID

21254098

DOI

10.1002/mus.21889

Scopus ID

2-s2.0-78751669175 (requires institutional sign-in at Scopus site)

Abstract

We report a patient who developed subacute facial-predominant numbness and anhidrosis, oral incoordination, and esophageal achalasia with resultant cachexia. Great auricular nerve biopsy showed extensive epineurial perivascular inflammatory infiltrates. Sensation, sweating, and swallowing improved with pulse intravenous methylprednisolone given over 5 years. We suggest that the patient's deficits, including achalasia, were due to an immune-mediated sensory and autonomic neuropathy and that, in such cases, pathologic studies of the great auricular nerve may be diagnostically informative.

Author List

Figueroa JJ, Engelstad JK, Spinner RJ, Dyck PJ

Author

Juan Jose Figueroa MD Assistant Professor in the Neurology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Aged
Body Temperature Regulation
Esophageal Achalasia
Functional Laterality
Humans
Immunotherapy
Male
Trigeminal Nerve Diseases