Skeletal muscle oxidative capacity in young and older women and men. J Appl Physiol (1985) 2000 Sep;89(3):1072-8
Date
08/24/2000Pubmed ID
10956353DOI
10.1152/jappl.2000.89.3.1072Scopus ID
2-s2.0-0034493131 (requires institutional sign-in at Scopus site) 154 CitationsAbstract
It has been suggested that a decline in skeletal muscle oxidative capacity is a general consequence of aging in humans. However, previous studies have not always controlled for the effects of varying levels of physical activity on muscle oxidative capacity. To test the hypothesis that, when matched for comparable habitual physical activity levels, there would be no age-related decline in the oxidative capacity of a locomotor muscle, the postexercise recovery time of phosphocreatine was compared in the tibialis anterior muscle of young [n = 19; 33.8 +/- 4.8 (SD) yr] and older [n = 18; 75.5 +/- 4.5 yr] healthy women and men of similar, relatively low, activity levels. The intramuscular metabolic measurements were accomplished by using phosphorus magnetic resonance spectroscopy. The results indicate that there was no age effect on the postexercise recovery time of phosphocreatine recovery, thus supporting the stated hypothesis. These data suggest that there is no requisite decline in skeletal muscle oxidative capacity with aging in humans, at least through the seventh decade.
Author List
Kent-Braun JA, Ng AVAuthor
Alexander V. Ng PhD Associate Professor in the Exercise Science department at Marquette UniversityMESH terms used to index this publication - Major topics in bold
AdultAged
Aged, 80 and over
Aging
Female
Humans
Magnetic Resonance Spectroscopy
Male
Middle Aged
Muscle, Skeletal
Oxygen Consumption
Phosphocreatine
Walking
