Anaphylaxis on reperfusion during liver transplantation with coagulopathy. Anesth Analg 2012 Sep;115(3):522-5
Date
06/07/2012Pubmed ID
22669344DOI
10.1213/ANE.0b013e31825d2bf4Scopus ID
2-s2.0-84865680695 (requires institutional sign-in at Scopus site) 4 CitationsAbstract
We present a case in which anaphylaxis on hepatic reperfusion during liver transplantation presented only with hypotension and coagulopathy. There were no cutaneous manifestations or clinical features distinguishing anaphylaxis from postreperfusion syndrome. The recipient regularly consumed seafood, and the organ donor died of anaphylaxis to shellfish. The trigger for anaphylaxis was postulated to be passive transfer of immunoglobulin to the recipient. Anesthesiologists should be notified of donor factors to anticipate anaphylaxis. In this report, we discuss coagulopathy of anaphylaxis and contrast it with disseminated intravascular coagulation.
Author List
Woehlck HJ, Johnson CP, Roza AM, Gottschall JL, Brumwell M, Cronin DCAuthors
Christopher P. Johnson MD Professor in the Surgery department at Medical College of WisconsinHarvey J. Woehlck MD Professor in the Anesthesiology department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
AdultAnaphylaxis
Blood Coagulation Disorders
Humans
Liver
Liver Transplantation
Male
Reperfusion
Tryptases