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Spatial regulation of translation through RNA localization. F1000 Biol Rep 2012;4:16

Date

08/23/2012

Pubmed ID

22912650

Pubmed Central ID

PMC3412389

DOI

10.3410/B4-16

Scopus ID

2-s2.0-84864939880 (requires institutional sign-in at Scopus site)   16 Citations

Abstract

RNA localization is a mechanism to post-transcriptionally regulate gene expression. Eukaryotic organisms ranging from fungi to mammals localize mRNAs to spatially restrict synthesis of specific proteins to distinct regions of the cytoplasm. In this review, we provide a general summary of RNA localization pathways in Saccharomyces cerevisiae, Xenopus, Drosophila and mammalian neurons.

Author List

Gonsalvez GB, Long RM

Author

Roy M. Long PhD Assistant Dean, Professor in the Medical School Regional Campuses department at Medical College of Wisconsin