Neural correlates of sensory and decision processes in auditory object identification. Nat Neurosci 2004 Mar;7(3):295-301
Date
02/18/2004Pubmed ID
14966525DOI
10.1038/nn1198Scopus ID
2-s2.0-1442348901 (requires institutional sign-in at Scopus site) 389 CitationsAbstract
Physiological studies of auditory perception have not yet clearly distinguished sensory from decision processes. In this experiment, human participants identified speech sounds masked by varying levels of noise while blood oxygenation signals in the brain were recorded with functional magnetic resonance imaging (fMRI). Accuracy and response time were used to characterize the behavior of sensory and decision components of this perceptual system. Oxygenation signals in a cortical subregion just anterior and lateral to primary auditory cortex predicted accuracy of sound identification, whereas signals in an inferior frontal region predicted response time. Our findings provide neurophysiological evidence for a functional distinction between sensory and decision mechanisms underlying auditory object identification. The present results also indicate a link between inferior frontal lobe activation and response-selection processes during auditory perception tasks.
Author List
Binder JR, Liebenthal E, Possing ET, Medler DA, Ward BDAuthor
Jeffrey R. Binder MD Professor in the Neurology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Acoustic StimulationAdult
Auditory Pathways
Auditory Perception
Brain Mapping
Cerebrovascular Circulation
Cognition
Decision Making
Female
Frontal Lobe
Functional Laterality
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Neuropsychological Tests
Pattern Recognition, Visual
Photic Stimulation
Reaction Time
Speech Perception
Temporal Lobe
