Magnetophysiologic and echocardiographic comparison of blocked atrial bigeminy and 2:1 atrioventricular block in the fetus. Heart Rhythm 2013 Aug;10(8):1192-8
Date
04/27/2013Pubmed ID
23619035Pubmed Central ID
PMC3757956DOI
10.1016/j.hrthm.2013.04.020Scopus ID
2-s2.0-84881245951 (requires institutional sign-in at Scopus site) 25 CitationsAbstract
BACKGROUND: Blocked atrial bigeminy (BAB) and second-degree atrioventricular block with 2:1 conduction block (2:1 AVB) both present as ventricular bradycardia and can be difficult to distinguish by echocardiography. Since the prognosis and clinical management of these rhythms are different, an accurate diagnosis is essential.
OBJECTIVE: To identify magnetic and mechanical heart rate and rhythm parameters that could reliably distinguish BAB from 2:1 AVB.
METHODS: A retrospective study of ten BAB and seven 2:1 AVB subjects was performed, using fMCG and pulsed Doppler ultrasound.
RESULTS: Distinguishing BAB from 2:1 AVB by using fMCG was relatively straightforward because in BAB the ectopic P wave (P') occurred early, resulting in a bigeminal (short-long) atrial rhythm. The normalized coupling interval of the ectopic beat (PP' of the blocked beat to PP of the conducted beat) was 0.29 ± 0.03. In contrast, the echocardiographic assessment of inflow-outflow gave a normalized mechanical coupling interval (AA'/AA) near 0.5, which made it difficult to distinguish BAB from 2:1 AVB. Heart rate distinguished most subjects with BAB from those with 2:1 AVB (82 ± 5.7 beats/min vs 69 ± 4.2 beats/min), but was not a completely reliable indicator. In most subjects, BAB alternated with sinus rhythm or other rhythms, resulting in complex heart rate and rhythm patterns.
CONCLUSIONS: Fetal BAB and 2:1 AV block can be difficult to distinguish using echocardiography because in many fetuses with BAB the mechanical rhythm does not accurately reflect the magnetic rhythm. fMCG provides a more reliable means of making a differential diagnosis.
Author List
Wiggins DL, Strasburger JF, Gotteiner NL, Cuneo B, Wakai RTAuthor
Janette F. Strasburger MD Professor in the Pediatrics department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Atrioventricular BlockBradycardia
Diagnosis, Differential
Echocardiography
Fetal Diseases
Fetal Heart
Fetus
Heart Atria
Heart Rate
Humans
Magnetocardiography
Retrospective Studies
Ultrasonography, Doppler, Pulsed