Subconjunctival antibiotics for acute postcataract extraction endophthalmitis--is it necessary? Am J Ophthalmol 2004 Jun;137(6):1120-1
Date
06/09/2004Pubmed ID
15183800DOI
10.1016/j.ajo.2003.12.042Scopus ID
2-s2.0-2942622117 (requires institutional sign-in at Scopus site) 21 CitationsAbstract
PURPOSE: To evaluate the efficacy of adjunctive subconjunctival antibiotic injection in the treatment of acute postcataract extraction endophthalmitis.
DESIGN: Retrospective cohort study.
METHODS: Patients who presented with hand motions or better vision and received subconjunctival antibiotics (SC+ group) were compared with those who did not (SC- group) in the treatment of acute postoperative endophthalmitis.
RESULTS: The rate of obtaining a final vision of 20/40 or better was 60% in the SC+ group (n = 25) compared with 72% in the SC- group (n = 18) (P =.69), and the mean change in logMAR was -1.36 (improvement) versus -1.34 (P =.93). Based on a linear regression model controlling for presenting vision, there was no statistical difference in the mean logMAR change between the two groups (P =.73).
CONCLUSION: Subconjunctival antibiotic injection as an adjunct to intravitreal antibiotics was unassociated with treatment benefit in patients with acute postoperative endophthalmitis presenting with vision of hand motions or better.
Author List
Iyer MN, Han DP, Yun HJ, Eastwood D, Kim JE, Connor TB, Wirostko WJ, Dev SAuthors
Thomas B. Connor MD Professor in the Ophthalmology and Visual Sciences department at Medical College of WisconsinWilliam Wirostko MD Professor in the Ophthalmology and Visual Sciences department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
Acute DiseaseAged
Anti-Bacterial Agents
Cataract Extraction
Chemotherapy, Adjuvant
Cohort Studies
Conjunctiva
Endophthalmitis
Eye Infections, Bacterial
Humans
Injections
Postoperative Complications
Retrospective Studies
Vitreous Body