Faculty Collaboration Database

Effect of phosphate group addition on the properties of denture base resins. J Prosthet Dent 2008 Oct;100(4):302-8

Date

10/17/2008

Pubmed ID

18922259

Pubmed Central ID

PMC2659143

DOI

10.1016/S0022-3913(08)60210-3

Scopus ID

2-s2.0-52049094192 (requires institutional sign-in at Scopus site)   59 Citations

Abstract

STATEMENT OF PROBLEM: Acrylic resins are prone to microbial adherence, especially by Candida albicans. Surface-charged resins alter the ionic interaction between the denture resin and Candida hyphae, and these resins are being developed as a means to reduce microbial colonization on the denture surface.

PURPOSE: The purpose of this study was to investigate the physical and mechanical properties of phosphate-containing polymethyl methacrylate resins for their suitability as a denture material.

MATERIAL AND METHODS: Using PMMA with cross-linker (Lucitone 199) as a control, 4 experimental groups containing various levels of phosphate with and without cross-linker were generated. The properties examined were impact strength, fracture toughness, wettability (contact angle), and resin bonding ability to denture teeth. Impact strength was tested in the Izod configuration (n=16), and fracture toughness (n=13) was measured using the single-edge notched bend test. Wettability was determined by calculating the contact angle of water on the material surface (n=12), while ISO 1567 was used for bonding ability (n=12). The data were analyzed by 1- and 2-way ANOVA (alpha=.05).

RESULTS: A trend of increased hydrophilicity, as indicated by lower contact angle, was observed with increased concentrations of phosphate. With regard to the other properties, no significant differences were found when compared with the control acrylic resin.

CONCLUSIONS: No adverse physical effect due to the addition of a phosphate-containing monomer was found in the acrylic denture resins. Additional mechanical and physical properties, biocompatibility, and clinical efficacy studies are needed to confirm the in vivo anti-Candida activity of these novel resins.

Author List

Puri G, Berzins DW, Dhuru VB, Raj PA, Rambhia SK, Dhir G, Dentino AR

Authors

David Berzins BS,PhD Graduate Program Director for Dental Biomaterials in the General Dental Sciences/Dental Biomaterials department at Marquette University
Andrew Dentino BS,DDS,PhD Professor & Program Director of Periodontics in the Surgical Sciences department at Marquette University

MESH terms used to index this publication - Major topics in bold

Acrylic Resins
Analysis of Variance
Dental Stress Analysis
Denture Bases
Humans
Hydrophobic and Hydrophilic Interactions
Materials Testing
Methacrylates
Phosphates
Polymethyl Methacrylate
Statistics, Nonparametric