Faculty Collaboration Database

Influence of music on the stress response in patients receiving mechanical ventilatory support: a pilot study. Am J Crit Care 2007 Mar;16(2):141-5

Date

02/27/2007

Pubmed ID

17322014

Scopus ID

2-s2.0-34247869733 (requires institutional sign-in at Scopus site)   41 Citations

Abstract

BACKGROUND: Music is considered an ideal therapy for reducing stress in patients receiving mechanical ventilation. Previous studies of the effect of music on stress in such patients have focused solely on indirect markers of the stress response rather than on serum biomarkers.

OBJECTIVE: To explore the influence of music on serum biomarkers of the stress response in patients receiving ventilatory support.

METHODS: A convenience sample of 10 patients receiving mechanical ventilation was recruited from an 11-bed medical intensive care unit. Patients were randomly assigned to listen to music or to rest quietly for 60 minutes. Levels of corticotropin, cortisol, epinephrine, and norepinephrine were measured 4 times during the 60 minutes.

RESULTS: The levels of the 4 biomarkers of the stress response did not differ significantly between patients who listened to music and patients who rested quietly, though the levels of corticotropin and cortisol showed interesting trends.

CONCLUSIONS: Additional research is needed with a larger sample size to evaluate further the influence of music on biochemical markers of the stress response in patients receiving mechanical ventilatory support. In future studies, confounding factors such as endotracheal suctioning and administration of medications that influence the stress response should be controlled for.

Author List

Chlan LL, Engeland WC, Anthony A, Guttormson J

Author

Jill Guttormson BSN,MS,PhD Assistant Professor in the College of Nursing department at Marquette University

MESH terms used to index this publication - Major topics in bold

Adrenocorticotropic Hormone
Aged
Biomarkers
Epinephrine
Female
Humans
Hydrocortisone
Intensive Care Units
Male
Middle Aged
Music Therapy
Norepinephrine
Pilot Projects
Respiration, Artificial
Stress, Psychological