Faculty Collaboration Database

The effect of movement rate and complexity on functional magnetic resonance signal change during pedaling. Motor Control 2012 Apr;16(2):158-75

Date

02/24/2012

Pubmed ID

22357094

DOI

10.1123/mcj.16.2.158

Scopus ID

2-s2.0-84861175973 (requires institutional sign-in at Scopus site)   33 Citations

Abstract

We used functional magnetic resonance imaging (fMRI) to record human brain activity during slow (30 RPM), fast (60 RPM), passive (30 RPM), and variable rate pedaling. Ten healthy adults participated. After identifying regions of interest, the intensity and volume of brain activation in each region was calculated and compared across conditions (p < .05). Results showed that the primary sensory and motor cortices (S1, M1), supplementary motor area (SMA), and cerebellum (Cb) were active during pedaling. The intensity of activity in these areas increased with increasing pedaling rate and complexity. The Cb was the only brain region that showed significantly lower activity during passive as compared with active pedaling. We conclude that M1, S1, SMA, and Cb have a role in modifying continuous, bilateral, multijoint lower extremity movements. Much of this brain activity may be driven by sensory signals from the moving limbs.

Author List

Mehta JP, Verber MD, Wieser JA, Schmit BD, Schindler-Ivens SM

Authors

Sheila Schindler-Ivens PhD Assistant Professor in the Physical Therapy department at Marquette University
Brian Schmit PhD Professor in the Biomedical Engineering department at Marquette University

MESH terms used to index this publication - Major topics in bold

Adult
Brain Mapping
Cerebellum
Female
Frontal Lobe
Functional Neuroimaging
Humans
Locomotion
Magnetic Resonance Imaging
Male
Middle Aged
Motor Cortex
Parietal Lobe