Prevalence of psychiatric disorders in 4 to 16-year-olds with Williams syndrome. Am J Med Genet B Neuropsychiatr Genet 2006 Sep 05;141B(6):615-22
Date
07/11/2006Pubmed ID
16823805Pubmed Central ID
PMC2561212DOI
10.1002/ajmg.b.30344Scopus ID
2-s2.0-33748946219 (requires institutional sign-in at Scopus site) 251 CitationsAbstract
The prevalence of a range of DSM-IV psychiatric disorders in a sample of 119 4-16-year-old children with Williams syndrome (WS) was assessed using a structured diagnostic interview with their parents. Most children (80.7%) met criteria for at least one DSM-IV diagnosis. The most prevalent diagnoses were Attention Deficit/Hyperactivity Disorder (ADHD; 64.7%) and Specific Phobia (53.8%). There was a significant shift in Predominant Type of ADHD as a function of CA, from Combined for the youngest group (ages 4-6 years) to Inattentive for the oldest group (ages 11-16 years). The prevalence of Generalized Anxiety Disorder (GAD) increased significantly with age. These findings are another step toward defining the behavioral phenotype of WS.
Author List
Leyfer OT, Woodruff-Borden J, Klein-Tasman BP, Fricke JS, Mervis CBAuthor
Bonita Klein-Tasman BA,MA,PhD Professor in the Psychology department at University of Wisconsin - MilwaukeeMESH terms used to index this publication - Major topics in bold
AdolescentChild
Child, Preschool
Female
Humans
Male
Mental Disorders
Prevalence
Williams Syndrome
