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Windows into development: historic, current, and future perspectives on transgenic zebrafish. Dev Biol 2003 Apr 01;256(1):1-17

Date

03/26/2003

Pubmed ID

12654288

DOI

10.1016/s0012-1606(02)00083-0

Scopus ID

2-s2.0-0037378352 (requires institutional sign-in at Scopus site)   165 Citations

Abstract

The recent explosion of transgenic zebrafish lines in the literature demonstrates the value of this model system for detailed in vivo analysis of gene regulation and morphogenetic movements. The optical clarity and rapid early development of zebrafish provides the ability to follow these events as they occur in live, developing embryos. This article will review the development of transgenic technology in zebrafish as well as the current and future uses of transgenic zebrafish to explore the dynamic environment of the developing vertebrate embryo.

Author List

Udvadia AJ, Linney E

Author

Ava Udvadia BS,PhD Associate Professor in the Biological Sciences department at University of Wisconsin - Milwaukee




MESH terms used to index this publication - Major topics in bold

Animals
Animals, Genetically Modified
Developmental Biology
Female
Gene Expression Regulation, Developmental
Gene Targeting
Genetic Engineering
History, 20th Century
History, 21st Century
Male
Zebrafish