Faculty Collaboration Database

Outcomes analysis of mandibular distraction osteogenesis for the treatment of Pierre Robin sequence. Plast Reconstr Surg 2013 Aug;132(2):419-421

Date

07/31/2013

Pubmed ID

23897339

DOI

10.1097/PRS.0b013e3182958a54

Scopus ID

2-s2.0-84881417102 (requires institutional sign-in at Scopus site)   68 Citations

Abstract

UNLABELLED: Mandibular distraction osteogenesis is an established technique used to treat infants with Pierre Robin sequence associated with severe airway obstruction. The authors present a 7-year retrospective review of all patients with Pierre Robin sequence treated with mandibular distraction osteogenesis. Recorded variables included improvements in apnea/hypopnea index and postintervention tracheostomy. Multiple preoperative variables were assessed for association with successful mandibular distraction osteogenesis or tracheostomy. Fifty patients were identified for this study. Four patients (8 percent) required tracheostomy after distraction. A Fisher's exact test demonstrated no statistical association of tracheostomy with prematurity, low birth weight, preoperative intubation, late intervention, genetic syndromes, cardiac abnormalities, pulmonary abnormalities, or gastrostomy tube. The absence of a cleft palate, gastroesophageal reflux disease, and need for Nissen fundoplication were associated with failure of distraction.

CLINICAL QUESTION/LEVEL OF EVIDENCE: Therapeutic, IV.

Author List

Murage KP, Tholpady SS, Friel M, Havlik RJ, Flores RL

Author

Robert Havlik MD Chair, Professor in the Plastic Surgery department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Airway Obstruction
Cohort Studies
Female
Follow-Up Studies
Humans
Infant
Male
Mandible
Osteogenesis, Distraction
Pierre Robin Syndrome
Retrospective Studies
Risk Assessment
Tracheostomy
Treatment Outcome