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Respiratory syncytial virus and pediatric liver transplant: one center's experience. Prog Transplant 2013 Sep;23(3):253-7

Date

09/03/2013

Pubmed ID

23996945

DOI

10.7182/pit2013446

Scopus ID

2-s2.0-84883420734 (requires institutional sign-in at Scopus site)   2 Citations

Abstract

Respiratory syncytial virus (RSV) is a ubiquitous virus responsible for acute infections of the respiratory tract in patients of all ages. RSV presents significant health risks to immunocompromised patients. Two patients, 1 before a liver transplant and 1 after a liver transplant, died of a severe RSV infection. Because of the high risk of death, we recommend expanding the criteria for palivizumab prophylaxis to 2 types of patients: (1) patients with chronic liver disease or who have received a liver transplant and are 24 months old or less and (2) transplant recipients with underlying pulmonary conditions who are less than 36 months old. Further research is indicated in pediatric solid-organ transplant centers to evaluate the effective management of RSV infection to prevent morbidity.

Author List

Lerret S, Mavis A, Biank V, Telega G

Authors

Stacee Lerret PhD Professor Hybrid in the Pediatrics department at Medical College of Wisconsin
Grzegorz W. Telega MD Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Biliary Atresia
Child, Preschool
Fatal Outcome
Humans
Immunocompromised Host
Infant
Liver Transplantation
Male
Respiratory Syncytial Virus Infections