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Successful autologous cord blood transplantation in a child with acquired severe aplastic anemia. Pediatr Transplant 2013 May;17(3):E104-7

Date

03/08/2013

Pubmed ID

23464883

Pubmed Central ID

PMC4174564

DOI

10.1111/petr.12068

Scopus ID

2-s2.0-84876743210   7 Citations

Abstract

Over 400 cases of pediatric SAA occur annually in the United States. A growing number of children with SAA may have had their stem cells harvested through cord blood collection. We describe a nine-yr-old male with SAA treated successfully with an autologous cord blood transplant following immunoablative chemotherapy. With the increasing number of people cryopreserving autologous cord blood, the use of autologous cord blood in the treatment of SAA might be considered as initial therapy. This case serves to discuss approaches to preparative therapy as well as the potential complications in this growing cohort of patients.

Author List

Buchbinder D, Hsieh L, Puthenveetil G, Soni A, Stites J, Huynh V, Kirov I, Neudorf S, Rubin E, Sender L, Torno L, Margolis D, Childs R, Moore T, Nugent D

Author

David A. Margolis MD Interim Chair, Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Anemia, Aplastic
Blood Banks
Child
Cord Blood Stem Cell Transplantation
Cryopreservation
Fetal Blood
Humans
Immunosuppressive Agents
Male
Transplantation Conditioning
Transplantation, Autologous
Treatment Outcome