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Hemophagocytic lymphohistiocytosis masquerading as progressive chronic lymphocytic leukemia. Leuk Res Rep 2013;2(1):4-6

Date

12/29/2013

Pubmed ID

24371766

Pubmed Central ID

PMC3850386

DOI

10.1016/j.lrr.2012.10.003

Scopus ID

2-s2.0-84878370734   5 Citations

Abstract

Hemophagocytic lymphohistiocytosis (HLH) is a potentially fatal syndrome characterized by a non-malignant expansion of the macrophage population in the setting of a heightened cytokine response with subsequent widespread hemophagocytosis. It can occur as either genetic or acquired forms; the latter of which frequently occurs in the setting of infection, autoimmune disease, or malignancy. We present the second known case of HLH associated Chronic Lymphocytic Leukemia (CLL) in the absence of infectious etiology and review the current literature.

Author List

Kilari D, Venci N, Friedberg J, Bennett JM

Author

Deepak Kilari MD Associate Professor in the Medicine department at Medical College of Wisconsin