Vasculitic neuropathies. Lancet Neurol 2014 Jan;13(1):67-82
Date
12/18/2013Pubmed ID
24331794DOI
10.1016/S1474-4422(13)70236-9Scopus ID
2-s2.0-84892152798 (requires institutional sign-in at Scopus site) 126 CitationsAbstract
The vasculitic neuropathies are a diverse group of disorders characterised by the acute-to-subacute onset of painful sensory and motor deficits that result from inflammatory destruction of nerve blood vessels and subsequent ischaemic injury. They are common in patients with primary systemic vasculitis and are seen in vasculitis secondary to disorders such as rheumatoid arthritis, viral infections, and diabetic inflammatory neuropathies. It is imperative that neurologists recognise these disorders to initiate treatment promptly and thereby prevent morbidity and mortality. To simplify the approach to patients with vasculitis of the peripheral nerves, a straightforward, dichotomous classification scheme can be used in which the vasculitic neuropathies are divided into two groups-nerve large arteriole vasculitis and nerve microvasculitis-on the basis of the size of the involved vessels. The size of the affected blood vessels correlates with the clinical course and prognosis in patients with vasculitic neuropathy.
Author List
Gwathmey KG, Burns TM, Collins MP, Dyck PJAuthor
Michael P. Collins MD Professor in the Neurology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AnimalsDiabetic Neuropathies
Humans
Nervous System Diseases
Vascular Diseases
Vasculitis
