Urinary heavy metals and associated medical conditions in the US adult population. Int J Environ Health Res 2012;22(2):105-18
Date
08/23/2011Pubmed ID
21854105DOI
10.1080/09603123.2011.605877Scopus ID
2-s2.0-84859196753 (requires institutional sign-in at Scopus site) 68 CitationsAbstract
Health effects of heavy metals have been widely investigated, but further evaluation is required to comprehensively delineate their toxicity. Using data from the 2007-2008 National Health and Nutrition Examination Survey, a multivariate logistic regression analysis was performed on 1,857 adults to examine the relationship between urinary heavy metals and various medical conditions. Cardiovascular diseases were correlated to cadmium (OR: 4.94, 95% CI: 1.48-16.56) and lead (OR: 5.32, 95% CI: 1.08-26.21). Asthma was related to tungsten (OR: 1.72, 95% CI: 1.15-2.59) and uranium (OR: 1.52, 95% CI: 1.01-2.28). Hepatotoxicity was associated with molybdenum (OR: 3.09, 95% CI: 1.24-7.73) and uranium (OR: 4.79, 95% CI: 1.74-13.19). Surprising inverse relationships occurred for excessive weight with lead (OR: 0.72, 95% CI: 0.52-0.98), reduced visual acuity with cobalt (OR: 0.65, 95% CI: 0.44-0.95) and cesium (OR: 0.52, 95% CI: 0.35-0.77). This study supports some previous evidence of potential relationships and provides insights for future research.
Author List
Mendy A, Gasana J, Vieira ERAuthor
Janvier Gasana MD, MPH, PhD Adjunct Associate Professor in the Institute for Health and Equity department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultAged
Aged, 80 and over
Arthritis
Cardiovascular Diseases
Cross-Sectional Studies
Environmental Monitoring
Environmental Pollutants
Epidemiological Monitoring
Female
Health Surveys
Humans
Liver Diseases
Lung Diseases
Male
Metals, Heavy
Middle Aged
Thyroid Diseases
United States
Visual Acuity
Young Adult
