Dynamically shimmed multivoxel 1H magnetic resonance spectroscopy and multislice magnetic resonance spectroscopic imaging of the human brain. Magn Reson Med 2007 Mar;57(3):587-91
Date
02/28/2007Pubmed ID
17326186DOI
10.1002/mrm.21141Scopus ID
2-s2.0-33847748646 (requires institutional sign-in at Scopus site) 38 CitationsAbstract
In vivo multivoxel Magnetic Resonance Spectroscopy (MRS) and multislice Magnetic Resonance Spectroscopic Imaging (MRSI) are extremely susceptible to poor homogeneity of the static magnetic field. Existing room-temperature (RT) shim technology can adequately optimize the B(0) homogeneity of local volumes, such as single voxels. However, the widespread global homogeneity required for in vivo spectral acquisitions from multiple volumes in the human brain cannot be attained with a single RT shim setting. Dynamic shim updating (DSU) allows for use of local RT shim B(0) homogeneity compensation capabilities in a global fashion. Here, by updating first- and second-order shims on a voxel- and slice-specific basis using a pre-emphasized DSU system, we present multivoxel MRS and multislice MRSI of the human brain. These results demonstrate that DSU can increase multivoxel MRS acquisition capabilities and significantly improve the quality of multislice MRSI data.
Author List
Koch KM, Sacolick LI, Nixon TW, McIntyre S, Rothman DL, de Graaf RAAuthor
Kevin M. Koch PhD Center Director, Professor in the Radiology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultBrain Mapping
Female
Humans
Image Processing, Computer-Assisted
Magnetic Resonance Spectroscopy
Male
Middle Aged
