Umbilical cord plasma and salivary insulin and leptin concentrations in AGA neonates: a preliminary report. J Matern Fetal Neonatal Med 2014 Nov;27(16):1716-8
Date
01/30/2014Pubmed ID
24471818DOI
10.3109/14767058.2014.887067Scopus ID
2-s2.0-84907841713 (requires institutional sign-in at Scopus site)Abstract
UNLABELLED: Background and objective: Insulin and leptin hormones are important regulators of food intake and energy balance. There is limited information about insulin and leptin hormones in neonates. This preliminary study aimed to investigate the concentrations of insulin and leptin in umbilical cord plasma and neonate's saliva and their relationships.
METHODS: Umbilical cord plasma and salivary samples were obtained from 13 healthy, appropriate for gestational age (AGA) neonates. Insulin and leptin concentrations in umbilical cord plasma and saliva were measured using the MILLIPLEX MAP® Human Metabolic Hormone Magnetic Bead Panel.
RESULTS: Insulin concentrations in umbilical cord plasma correlates positively and significantly with leptin concentrations in umbilical cord plasma (r = 0.55, p = 0.04).
CONCLUSIONS: More research is needed to explore the relationships between insulin and leptin hormones in neonate's saliva.
Author List
Seal N, Siddiqui DS, Seal J, Bernhard KA, Williams SAuthor
Nuananong Seal PhD Assistant Professor in the Nursing department at University of Wisconsin - MilwaukeeMESH terms used to index this publication - Major topics in bold
Cross-Sectional StudiesFemale
Fetal Blood
Humans
Infant, Newborn
Insulin
Leptin
Male
Prospective Studies
Saliva
