Faculty Collaboration Database

Primary sclerosing cholangitis treated by endoscopic biliary dilation: review and long-term follow-up evaluation. Curr Gastroenterol Rep 2006 Apr;8(2):147-55

Date

03/15/2006

Pubmed ID

16533478

DOI

10.1007/s11894-006-0011-y

Scopus ID

2-s2.0-33645537832 (requires institutional sign-in at Scopus site)   25 Citations

Abstract

Primary sclerosing cholangitis (PSC) is an important cause of chronic liver disease. We review the management of PSC and report a 20-year follow-up of our initial 10 patients. This is the longest detailed follow-up of a group of PSC patients to date. We discuss the clinical course and results of endoscopic management in these patients and relate these data to management of PSC in general. We compare the actual survival of these patients to predicted survival scores based on the Mayo multicenter survival model. Although our patients presented with cholangitis, which typically reflects advanced stages of liver disease, their survival compares favorably with expected survival in unselected PSC patients. Endoscopic balloon dilation of PSC patients presenting with biliary strictures and cholangitis may have long-term benefit in addition to short-term symptomatic relief.

Author List

Johnson GK, Saeian K, Geenen JE

Author

Kia Saeian MD Professor in the Medicine department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adult
Aged
Bile Duct Neoplasms
Bile Ducts, Intrahepatic
Biliary Tract Diseases
Cause of Death
Cholangiocarcinoma
Cholangitis, Sclerosing
Evaluation Studies as Topic
Female
Follow-Up Studies
Humans
Longitudinal Studies
Male
Middle Aged
Survival Analysis