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The effect of acute pain crisis on exhaled nitric oxide levels in children with sickle cell disease. Pediatr Blood Cancer 2008 Jan;50(1):111-3

Date

04/19/2006

Pubmed ID

16619223

DOI

10.1002/pbc.20872

Scopus ID

2-s2.0-36849095988   4 Citations

Abstract

Exhaled nitric oxide (FE(NO)) has been shown to be decreased in children with sickle cell disease. We sought to evaluate the effect of sickle cell vaso-occlusive crisis (VOC) on FE(NO) levels. We measured FE(NO) levels in 42 children with sickle cell disease, 29 in their baseline health and 13 during an acute VOC. There was no difference in FE(NO) levels between children at baseline (15.12 +/- 9.32 ppb) and those during an acute VOC (15.68 +/- 7.26 ppb; P = 0.794). FE(NO) is not a useful marker of acute VOC in children with sickle cell disease.

Author List

Pawar SS, Panepinto JA, Brousseau DC

Authors

David Brousseau MD Chief, Professor in the Pediatrics department at Medical College of Wisconsin
Sachin S. Pawar MD Chief, Associate Professor in the Otolaryngology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Acute Disease
Adolescent
Anemia, Sickle Cell
Breath Tests
Child
Child, Preschool
Female
Humans
Lung Diseases
Male
Nitric Oxide
Pain