Faculty Collaboration Database

Probability of survival based on etiology of cardiopulmonary arrest in pediatric patients. Paediatr Anaesth 2011 Aug;21(8):834-40

Date

01/05/2011

Pubmed ID

21199129

DOI

10.1111/j.1460-9592.2010.03479.x

Scopus ID

2-s2.0-79960017746 (requires institutional sign-in at Scopus site)   33 Citations

Abstract

OBJECTIVE: To aggregate data across institutions to identify, characterize, and differentiate potential survivors from nonsurvivors based on etiology of event.

AIM: To evaluate the association of the cardiopulmonary resuscitation (CPR) duration and probability of survival (Ps), stratified by etiology of arrest.

BACKGROUND: In-hospital cardiac arrests occur in 2-6% of pediatric patients with poor survival rates resulting in significant expenditures of time and resources.

METHODS: Retrospective data from six pediatric hospitals on patients suffering from pulseless cardiac arrests receiving CPR for over one minute were analyzed. Data included demographics, reason for code, precardiac arrest diagnosis, devices and treatment, management strategies during cardiac arrest, compression duration, outcome at hospital discharge, and neurologic outcome of survivors at hospital discharge. Results of logistic regression analysis generated predicated probabilities of survival for duration of compression. Patients were stratified by cardiac-induced cardiac arrests (CICA) and respiratory-induced cardiac arrest (RICA).

RESULTS: A total of 257 patients were included, and 27% of CICA and 35% of RICA patients survived to hospital discharge. Ps was initially lower for the CICA patients (Ps at 1 min = 29%) and remained constant (Ps at 60 min = 25%). RICA patients'Ps was higher initially (Ps at 1 min = 62%) but demonstrated a dramatic drop within the first 60 min of CPR (Ps at 60 min = 0.2%).

CONCLUSIONS: Probability of survival curves based on duration of CPR was statistically significantly different for CICA patients compared to RICA patients.

Author List

Berens RJ, Cassidy LD, Matchey J, Campbell D, Colpaert KD, Welch T, Lawson M, Peterson C, O'Flynn J, Dearth M, Tieves KS

Authors

Richard J. Berens MD Professor in the Anesthesiology department at Medical College of Wisconsin
Laura Cassidy PhD Associate Dean, Professor in the Institute for Health and Equity department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adolescent
Cardiopulmonary Resuscitation
Child
Child, Preschool
Cognition Disorders
Critical Care
Female
Heart Arrest
Hospital Mortality
Humans
Infant
Infant, Newborn
Intraoperative Complications
Logistic Models
Male
Nervous System Diseases
Probability
Respiratory Physiological Phenomena
Retrospective Studies
Survival Rate
Treatment Outcome
Young Adult