Superficial hemosiderotic lymphovascular malformation (hobnail hemangioma): a report of six cases. Pediatr Dermatol 2014;31(3):281-5
Date
03/08/2014Pubmed ID
24601986DOI
10.1111/pde.12294Scopus ID
2-s2.0-84899534206 (requires institutional sign-in at Scopus site) 11 CitationsAbstract
Hobnail hemangioma (HH), initially termed targetoid hemosiderotic hemangioma, is a rare, often solitary lesion classically characterized by a central brown or violaceous papulonodule surrounded at times by an ecchymotic halo. This lesion is typically found on the trunk or limbs of children or young to middle-aged adults. Numerous case reports have found HHs to have a reproducible histologic appearance. Although the exact histogenesis of these lesions is unknown, multiple recent immunohistochemical studies suggest a lymphatic origin of these lesions. We present six cases of children with HHs with classic histology but with variability in their clinical appearance. Because the clinical presence of a targetoid halo is inconsistent and the hobnail phenomenon is not specific, we favor the designation of superficial hemosiderotic lymphovascular malformation instead of HH or targetoid hemosiderotic hemangioma as a more unifying term for this rare clinical entity. By eliminating confounding terminologies (in this case, incorporation of "hemangioma" in the name of this entity), we also hope to encourage a swifter change in practice to move away from erroneous diagnostic considerations.
Author List
Joyce JC, Keith PJ, Szabo S, Holland KEAuthor
Kristen E. Holland MD Associate Professor in the Dermatology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdolescentBiopsy
Child
Child, Preschool
Diagnosis, Differential
Ecchymosis
Female
Hemangioma
Hemosiderin
Humans
Male
Skin
Skin Neoplasms
