Faculty Collaboration Database

Office probing for treatment of nasolacrimal duct obstruction in infants. J AAPOS 2014 Feb;18(1):26-30

Date

02/27/2014

Pubmed ID

24568978

Pubmed Central ID

PMC3936253

DOI

10.1016/j.jaapos.2013.10.016

Scopus ID

2-s2.0-84894522104 (requires institutional sign-in at Scopus site)   25 Citations

Abstract

PURPOSE: To determine whether demographic or clinical factors are associated with the outcome of office-based nasolacrimal duct probing for the treatment of congenital nasolacrimal duct obstruction (NLDO).

METHODS: In two multicenter prospective studies, 384 eyes of 304 children aged 6 to <15 months with NLDO underwent a nasolacrimal duct probing performed in the office using topical anesthesia. Treatment success, defined as no clinical signs of NLDO (epiphora, increased tear lake, or mucous discharge) and no reoperation, was assessed 1 month after probing in one study and 6 months after probing in the other study. Data from both studies were pooled to evaluate associations between baseline characteristics and treatment success.

RESULTS: Office probing was successful in 75% of eyes overall (95% CI, 70%-80%). The procedure was less successful in eyes of children with bilateral NLDO compared with unilateral NLDO (63% vs 80%; relative risk = 0.78 [95% CI, 0.66-0.92]) and in eyes that had 2 or 3 clinical signs of NLDO compared with one (71% vs 83%; relative risk = 0.88 [95% CI, 0.81-0.96]). Treatment success did not appear to be related to age, specific clinical signs of NLDO, prior treatment, or research study.

CONCLUSIONS: Performing nasolacrimal duct probing in the office successfully treats NLDO in the majority of cases in children aged 6 to <15 months. The success rate is lower with bilateral disease or when more than one clinical sign of NLDO is present.

Author List

Miller AM, Chandler DL, Repka MX, Hoover DL, Lee KA, Melia M, Rychwalski PJ, Silbert DI, Pediatric Eye Disease Investigator Group, Beck RW, Crouch ER 3rd, Donahue S, Holmes JM, Quinn GE, Sala NA, Schloff S, Wallace DK, Foster NC, Frick KD, Golden RP, Lambert SR, Tien DR, Weakley DR Jr

Author

Alexander Joseph Khammar MD Associate Professor in the Ophthalmology and Visual Sciences department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Ambulatory Surgical Procedures
Anesthesia, Local
Dacryocystorhinostomy
Female
Humans
Infant
Intubation
Lacrimal Duct Obstruction
Male
Nasolacrimal Duct
Ophthalmologic Surgical Procedures
Prospective Studies
Treatment Outcome