Spontaneous lateral sphenoid cephaloceles: anatomic factors contributing to pathogenesis and proposed classification. AJNR Am J Neuroradiol 2014 Apr;35(4):784-9
Date
10/05/2013Pubmed ID
24091443Pubmed Central ID
PMC7965830DOI
10.3174/ajnr.A3744Scopus ID
2-s2.0-84898477050 (requires institutional sign-in at Scopus site) 54 CitationsAbstract
Spontaneous lateral sphenoid cephaloceles arise from bony defects in the lateral sphenoid, in the absence of predisposing factors such as trauma, surgery, mass, or congenital skull base malformation. We reviewed CT and MR imaging findings and clinical data of 26 patients with spontaneous lateral sphenoid cephaloceles to better understand anatomic contributions to pathogenesis, varying clinical and imaging manifestations, and descriptive terminology. Two types of spontaneous lateral sphenoid cephaloceles were identified. In 15 of 26 patients, a type 1 spontaneous lateral sphenoid cephalocele was noted, herniating into a pneumatized lateral recess of the sphenoid sinus, and typically presenting with CSF leak and/or headache. In 11 of 26 patients, a type 2 spontaneous lateral sphenoid cephalocele was noted, isolated to the greater sphenoid wing without extension into the sphenoid sinus, presenting with seizures, headaches, meningitis, cranial neuropathy, or detected incidentally. All patients had sphenoid arachnoid pits, and 61% of patients had an empty or partially empty sella, suggesting that altered CSF dynamics may play a role in their genesis.
Author List
Settecase F, Harnsberger HR, Michel MA, Chapman P, Glastonbury CMAuthor
Michelle A. Michel MD Adjunct Professor in the Radiology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AdultAged
Arachnoid
Cerebrospinal Fluid Leak
Empty Sella Syndrome
Encephalocele
Female
Humans
Magnetic Resonance Imaging
Male
Middle Aged
Retrospective Studies
Sphenoid Bone
Tomography, X-Ray Computed
Young Adult
