Lacosamide-induced atrial tachycardia in a child with hypoplastic left-heart syndrome: the importance of assessing additional proarrhythmic risks. Cardiol Young 2015 Apr;25(4):806-9
Date
07/22/2014Pubmed ID
25046031DOI
10.1017/S1047951114001188Scopus ID
2-s2.0-84924483315 (requires institutional sign-in at Scopus site) 8 CitationsAbstract
Antiepileptic medications have been reported to cause disturbances in cardiac conduction. Lacosamide decreases seizure burden by modulating sodium channels. Although it has been demonstrated to have few side effects, there have been reports of clinically significant cardiac conduction disturbances. We report the case of a child with hypoplastic left-heart syndrome and well-controlled multifocal atrial tachycardia who developed haemodynamically significant atrial tachycardia after receiving two doses of lacosamide.
Author List
Loomba RS, Singh AK, Kovach J, Gudausky TMAuthors
Todd M. Gudausky MD Associate Professor in the Pediatrics department at Medical College of WisconsinJoshua Kovach MD Associate Professor in the Pediatrics department at Medical College of Wisconsin
Anoop K. Singh MD Associate Professor in the Pediatrics department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
AcetamidesAnticonvulsants
Arrhythmias, Cardiac
Child, Preschool
Comorbidity
Humans
Hypoplastic Left Heart Syndrome
Isoxazoles
Male
Piracetam
Seizures
Tachycardia, Sinus
Treatment Outcome