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Lacosamide-induced atrial tachycardia in a child with hypoplastic left-heart syndrome: the importance of assessing additional proarrhythmic risks. Cardiol Young 2015 Apr;25(4):806-9

Date

07/22/2014

Pubmed ID

25046031

DOI

10.1017/S1047951114001188

Scopus ID

2-s2.0-84924483315 (requires institutional sign-in at Scopus site)   8 Citations

Abstract

Antiepileptic medications have been reported to cause disturbances in cardiac conduction. Lacosamide decreases seizure burden by modulating sodium channels. Although it has been demonstrated to have few side effects, there have been reports of clinically significant cardiac conduction disturbances. We report the case of a child with hypoplastic left-heart syndrome and well-controlled multifocal atrial tachycardia who developed haemodynamically significant atrial tachycardia after receiving two doses of lacosamide.

Author List

Loomba RS, Singh AK, Kovach J, Gudausky TM

Authors

Todd M. Gudausky MD Associate Professor in the Pediatrics department at Medical College of Wisconsin
Joshua Kovach MD Associate Professor in the Pediatrics department at Medical College of Wisconsin
Anoop K. Singh MD Associate Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Acetamides
Anticonvulsants
Arrhythmias, Cardiac
Child, Preschool
Comorbidity
Humans
Hypoplastic Left Heart Syndrome
Isoxazoles
Male
Piracetam
Seizures
Tachycardia, Sinus
Treatment Outcome