Faculty Collaboration Database

Extrapleural pneumonectomy in children. J Pediatr Surg 2006 Oct;41(10):1738-42

Date

10/03/2006

Pubmed ID

17011280

DOI

10.1016/j.jpedsurg.2006.05.063

Scopus ID

2-s2.0-33748986541 (requires institutional sign-in at Scopus site)   12 Citations

Abstract

BACKGROUND/PURPOSE: Extrapleural pneumonectomy (EPP) is an en bloc resection of the pleura, lung, diaphragm, and pericardium. EPP in the pediatric population has not been reported in the literature. We report our experience of using EPP in children to treat a variety of malignancies that involve the pleural surface.

METHODS: We performed a retrospective review of all children treated through EPP at our institution. Data were obtained from patient charts and a pediatric database. All patients underwent en bloc resection of the pleura, lung, diaphragm, and pericardium and reconstruction.

RESULTS: Four patients underwent EPP from 2000 to 2004 for inflammatory myofibroblastic tumor, spindle cell sarcoma, metastatic neuroblastoma, and malignant mesothelioma. The patients' ages were from 6 to 11 years. The patient with metastatic neuroblastoma had recurrent disease in the left chest 1 year after EPP and died of sepsis; the patient with mesothelioma died of disease extension into the abdomen 1.5 years later. The other 2 patients are free of disease.

CONCLUSIONS: EPP can be performed with curative intent in selected pediatric patients with pleural-based malignancies. EPP should be included in the armamentarium of the pediatric thoracic surgeon and evaluated in larger studies.

Author List

Flores RM, Su W, Lal D, Rusch VW, La Quaglia MP

Author

Dave Lal MD, MPH Chief, Professor in the Surgery department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Abdominal Neoplasms
Child
Diaphragm
Female
Granuloma, Plasma Cell
Humans
Lung
Male
Mesothelioma
Neuroblastoma
Pericardium
Pleura
Pleural Diseases
Pleural Neoplasms
Pneumonectomy
Retrospective Studies
Sarcoma