Medical College of Wisconsin
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How we treat early systemic prostate cancer in older men. J Geriatr Oncol 2014 Oct 01;5(4):337-42



Pubmed ID




Scopus ID

2-s2.0-84908256130   6 Citations


With the aging of our population, the prevalence of prostate cancer is anticipated to rise dramatically. Consequently, physicians will be confronted with the challenges of managing prostate cancer and treatment side effects in older men. The maintenance of mobility and functional independence, which are fundamental goals of the aging patient with cancer, should not be overlooked when choosing treatments and their toxicities focused on cancer control. Consistent with the SIOG (International Society of Geriatric Oncology) guidelines, we recommend standard approaches for older patients with prostate cancer who are fit. Vulnerable patients should also receive standard treatment, provided their health status can be maintained with appropriate interventions. Treatment for frail patients should be adapted to their health status and supportive care interventions should be considered. Individualized treatment plans should take into account patient's remaining life-expectancy from coexisting comorbidities and disability, aggressiveness of the prostate cancer, treatment preferences as well as potential adverse effects of treatment.

Author List

Kilari D, Dale W, Mohile SG


Deepak Kilari MD Associate Professor in the Medicine department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Aged, 80 and over
Health Services for the Aged
Prostatic Neoplasms