Obesity and weight loss in the treatment and prevention of osteoarthritis. PM R 2012 May;4(5 Suppl):S59-67
Date
06/01/2012Pubmed ID
22632704Pubmed Central ID
PMC3623013DOI
10.1016/j.pmrj.2012.01.005Scopus ID
2-s2.0-84861416455 (requires institutional sign-in at Scopus site) 155 CitationsAbstract
Obesity is associated with an increasing prevalence of musculoskeletal complaints and pain. Obesity is a major risk factor for osteoarthritis (OA), and pain can manifest in load-bearing and nonload-bearing joints. The lumbar spine and the knee are 2 primary sites for pain onset in the obese patient. Irrespective of the weight loss method, reduction of body fat can lower the mechanical and inflammatory stressors that contribute to OA. Single or combined methods of weight loss including exercise, dietary modification, medications, and bariatric surgery are associated with lower joint pain and increased physical function. Methods of weight loss or maintenance in early years may reduce the life exposure of joints to the obesity induced stressors on load bearing joints.
Author List
Vincent HK, Heywood K, Connelly J, Hurley RWAuthor
Robert W. Hurley MD, PhD Adjunct Professor of Anesthesiology and CTSI in the Anesthesiology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Biomechanical PhenomenaDiet
Exercise Therapy
Gait
Humans
Muscle Strength
Obesity
Osteoarthritis
Risk Factors