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Obesity and weight loss in the treatment and prevention of osteoarthritis. PM R 2012 May;4(5 Suppl):S59-67

Date

06/01/2012

Pubmed ID

22632704

Pubmed Central ID

PMC3623013

DOI

10.1016/j.pmrj.2012.01.005

Scopus ID

2-s2.0-84861416455 (requires institutional sign-in at Scopus site)   155 Citations

Abstract

Obesity is associated with an increasing prevalence of musculoskeletal complaints and pain. Obesity is a major risk factor for osteoarthritis (OA), and pain can manifest in load-bearing and nonload-bearing joints. The lumbar spine and the knee are 2 primary sites for pain onset in the obese patient. Irrespective of the weight loss method, reduction of body fat can lower the mechanical and inflammatory stressors that contribute to OA. Single or combined methods of weight loss including exercise, dietary modification, medications, and bariatric surgery are associated with lower joint pain and increased physical function. Methods of weight loss or maintenance in early years may reduce the life exposure of joints to the obesity induced stressors on load bearing joints.

Author List

Vincent HK, Heywood K, Connelly J, Hurley RW

Author

Robert W. Hurley MD, PhD Adjunct Professor of Anesthesiology and CTSI in the Anesthesiology department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Biomechanical Phenomena
Diet
Exercise Therapy
Gait
Humans
Muscle Strength
Obesity
Osteoarthritis
Risk Factors