Faculty Collaboration Database

Sensitivity and specificity of memory and naming tests for identifying left temporal-lobe epilepsy. Appl Neuropsychol Adult 2015;22(3):189-96

Date

09/27/2014

Pubmed ID

25258176

DOI

10.1080/23279095.2014.895366

Scopus ID

2-s2.0-84928824628 (requires institutional sign-in at Scopus site)   12 Citations

Abstract

The sensitivity and specificity of the Selective Reminding Test (SRT) Delayed Recall, Wechsler Memory Scale (WMS) Logical Memory, the Boston Naming Test (BNT), and two nonverbal memory measures for detecting lateralized dysfunction in association with side of seizure focus was examined in a sample of 143 patients with left or right temporal-lobe epilepsy (TLE). Scores on the SRT and BNT were statistically significantly lower in the left TLE group compared with the right TLE group, whereas no group differences emerged on the Logical Memory subtest. No significant group differences were found with nonverbal memory measures. When the SRT and BNT were both entered as predictors in a logistic regression, the BNT, although significant, added minimal value to the model beyond the variance accounted for by the SRT Delayed Recall. Both variables emerged as significant predictors of side of seizure focus when entered into separate regressions. Sensitivity and specificity of the SRT and BNT ranged from 56% to 65%. The WMS Logical Memory and nonverbal memory measures were not significant predictors of the side of seizure focus.

Author List

Umfleet LG, Janecek JK, Quasney E, Sabsevitz DS, Ryan JJ, Binder JR, Swanson SJ

Authors

Jeffrey R. Binder MD Professor in the Neurology department at Medical College of Wisconsin
Julie K. Janecek PhD Associate Professor in the Neurology department at Medical College of Wisconsin
Sara J. Swanson PhD Chief, Professor in the Neurology department at Medical College of Wisconsin
Laura Umfleet PsyD Associate Professor in the Neurology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adult
Epilepsy, Temporal Lobe
Female
Functional Laterality
Humans
Male
Memory Disorders
Middle Aged
Names
Neuropsychological Tests
Regression Analysis
Sensitivity and Specificity
Verbal Learning
Wechsler Scales