Hypercortisolemia and infection. Infect Dis Clin North Am 2007 Sep;21(3):639-57, viii
Date
09/11/2007Pubmed ID
17826616DOI
10.1016/j.idc.2007.06.001Scopus ID
2-s2.0-34548437448 (requires institutional sign-in at Scopus site) 49 CitationsAbstract
Hypercortisolemia is a condition involving a prolonged excess of serum levels of cortisol that can develop as a result of disregulatory abnormalities in the hypothalamic-pituitary-adrenal axis or from exogenous-source steroids. Hypercortisolemia induces a state of immunocompromise that predisposes the patient to various bacterial, viral, fungal, and parasitic infections. To ensure optimal management of hypercortisolemia, the primary clinician must be cognizant of its different causes and aware of the different infections associated with cortisol excess. In the hypercortisolemic patient, it is necessary to restore normal cortisol levels to reduce the risk of infection or to improve the control and cure of established infection.
Author List
Fareau GG, Vassilopoulou-Sellin RAuthor
Gilbert G. Fareau MD Associate Professor in the Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
Cushing SyndromeHumans
