Neuropsychological findings in a case of punding before and after cessation of pramipexole. Clin Neuropsychol 2015;29(1):166-78
Date
02/07/2015Pubmed ID
25658417DOI
10.1080/13854046.2015.1005674Scopus ID
2-s2.0-84929025034 (requires institutional sign-in at Scopus site) 1 CitationAbstract
Clinical neuropsychologists are well trained to recognize neurological and psychiatric conditions that impact behavior, but tend to have less familiarity with iatrogenic consequences of various pharmacological treatments. One such consequence is the development of an impulse control disorder (ICD), which can result from treatment with dopamine agonists. Knowledge of ICDs is important because they can mimic obsessive-compulsive disorder, mania, or the behavioral variant of frontotemporal dementia. The current case examines a patient who developed punding, which is a type of ICD characterized by repetitive behavior, as a result of treatment with pramipexole. Neuropsychological testing was conducted before and after cessation of pramipexole, and showed that the removal of the medication was consistent with improvement in frontal-subcortical-mediated cognitive functions. Findings suggest that neuropsychologists should be familiar with the symptoms of ICDs and incorporate such knowledge into their case conceptualizations.
Author List
Larson ERAuthor
Eric Larson PhD Associate Professor in the Psychiatry and Behavioral Medicine department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
BenzothiazolesCompulsive Behavior
Dopamine Agonists
Humans
Male
Middle Aged
Parkinson Disease