Medical College of Wisconsin
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Neuropsychological findings in a case of punding before and after cessation of pramipexole. Clin Neuropsychol 2015;29(1):166-78

Date

02/07/2015

Pubmed ID

25658417

DOI

10.1080/13854046.2015.1005674

Scopus ID

2-s2.0-84929025034 (requires institutional sign-in at Scopus site)   1 Citation

Abstract

Clinical neuropsychologists are well trained to recognize neurological and psychiatric conditions that impact behavior, but tend to have less familiarity with iatrogenic consequences of various pharmacological treatments. One such consequence is the development of an impulse control disorder (ICD), which can result from treatment with dopamine agonists. Knowledge of ICDs is important because they can mimic obsessive-compulsive disorder, mania, or the behavioral variant of frontotemporal dementia. The current case examines a patient who developed punding, which is a type of ICD characterized by repetitive behavior, as a result of treatment with pramipexole. Neuropsychological testing was conducted before and after cessation of pramipexole, and showed that the removal of the medication was consistent with improvement in frontal-subcortical-mediated cognitive functions. Findings suggest that neuropsychologists should be familiar with the symptoms of ICDs and incorporate such knowledge into their case conceptualizations.

Author List

Larson ER

Author

Eric Larson PhD Associate Professor in the Psychiatry and Behavioral Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Benzothiazoles
Compulsive Behavior
Dopamine Agonists
Humans
Male
Middle Aged
Parkinson Disease