Loosening pain's grip by tightening TRPV1-TRPA1 interactions. Neuron 2015 Feb 18;85(4):661-3
Date
02/20/2015Pubmed ID
25695265DOI
10.1016/j.neuron.2015.02.004Scopus ID
2-s2.0-84925432939 (requires institutional sign-in at Scopus site) 8 CitationsAbstract
TRPA1 and TRPV1 are ion channels crucial for pain sensation. In this issue of Neuron, Weng et al. (2015) demonstrate that the activity of TRPA1-TRPV1 heteromers is governed by Tmem100 and that disabling Tmem100 may be a novel pharmacologic strategy to combat pain.
Author List
Weyer AD, Stucky CLAuthor
Cheryl L. Stucky PhD Professor in the Cell Biology, Neurobiology and Anatomy department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AnimalsHumans
Male
Membrane Proteins
Pain
TRPA1 Cation Channel
TRPV Cation Channels
Transient Receptor Potential Channels
