Faculty Collaboration Database

Stenting and angioplasty for idiopathic intracranial hypertension: a case series with clinical, angiographic, ophthalmological, complication, and pressure reporting. J Neuroimaging 2015;25(1):72-80

Date

03/03/2015

Pubmed ID

25729814

DOI

10.1111/jon.12072

Scopus ID

2-s2.0-84920989039 (requires institutional sign-in at Scopus site)   40 Citations

Abstract

BACKGROUND: Previous studies have demonstrated that cerebral dural sinus stenosis (DSS) may be a potential patho-physiological cause of idiopathic intracranial hypertension (IIH). Endovascular therapy for DSS is emerging as a potential alternative to treat IIH. Here, we present the results of our case series.

METHOD: We prospectively collected angiographic and manometric data on patients that underwent angioplasty/stenting for IIH. All patients had failed maximal medical therapy (MMT) and had confirmed sinus stenosis. Demographic, clinical and radiological presentation, and outcomes were collected retrospectively.

RESULTS: A total of 18 patients underwent 25 procedures. Demographics revealed a mean age of 30 (range 15-59), 83% (15/18) were female, 72% (13/18) were white, and mean body mass index of 36 (range 23-59.2). All patients presented with classic IIH. Symptom improvement or resolution was reported in 94% (17/18) of patients. All patients had resolution and/or stabilization/improvement of their papilledema. Headaches related to increased pressure improved in 56% (10/18). Re-stenosis and retreatment occurred in 33% (6/18). No procedural related complications were reported.

CONCLUSION: Dural sinus angioplasty and stenting is relatively safe, feasible, and clinically efficacious for patients with symptomatic sinus stenosis who have failed standard therapy. The long-term durability of patency and clinical improvement remains unknown.

Author List

Teleb MS, Cziep ME, Issa M, Lazzaro M, Asif K, Hong SH, Lynch JR, Fitzsimmons BF, Remler BF, Zaidat OO

Author

Bernd F. Remler MD Professor in the Neurology department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Adult
Angioplasty
Blood Vessel Prosthesis
Cerebral Angiography
Combined Modality Therapy
Female
Humans
Intracranial Hypertension
Intracranial Pressure
Male
Middle Aged
Pseudotumor Cerebri
Stents
Treatment Outcome
Vision Disorders
Young Adult