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Predictors of need for mechanical ventilation at discharge after tracheostomy in the PICU. Pediatr Pulmonol 2016 Jan;51(1):53-9



Pubmed ID




Scopus ID

2-s2.0-84977473689   3 Citations


BACKGROUND: The objective of this study was to determine factors predictive of need for mechanical ventilation (MV) upon discharge from the pediatric intensive care unit (PICU) among patients who receive a tracheostomy during their stay.

METHODS: This was a retrospective cohort study using the Virtual PICU Systems (VPS) database. Patients <18 years old admitted between 2009-2011 who required MV for at least 3 days and received a tracheostomy during their PICU stay were included.

RESULTS: A total of 680 pediatric patients from 74 PICUs were included, of whom 347 (51%) remained on MV at the time of PICU discharge. Neonates (30/38, 79%) and infants (129/203, 64%) required MV at PICU discharge after tracheostomy more often than adolescents (66/141, 47%) and children (122/298, 41%). Time on MV pre-tracheostomy was longer among those who required MV at discharge (median 18.3 vs. 13.8 days, Pa??<a??0.0001); however, number of failed extubations was similar (median 1 for both groups, Pa??=a??0.97). On mixed-effects multivariable regression analysis, the age categories of neonate (ORa??2.9, 95%CI 1.1-7.6, Pa??=a??0.03), and infant (ORa??1.7, 95%CI 1.1-2.8, Pa??=a??0.03), and ventilator days prior to tracheostomy (ORa??1.01, 95%CI 1.0-1.02, Pa??=a??0.01) were significantly associated with increased odds of MV upon PICU discharge, while being a trauma admission was associated with decreased odds (ORa??0.45, 95%CI 0.28-0.73, Pa??=a??0.001).

CONCLUSIONS: Younger patients and those with prolonged courses of MV prior to tracheostomy are more likely to continue to need MV upon PICU discharge.

Author List

McCrory MC, Lee KJ, Scanlon MC, Wakeham MK


K Jane Lee MD Associate Professor in the Pediatrics department at Medical College of Wisconsin
Matthew C. Scanlon MD Professor in the Pediatrics department at Medical College of Wisconsin
Martin K. Wakeham MD Professor in the Pediatrics department at Medical College of Wisconsin

MESH terms used to index this publication - Major topics in bold

Child, Preschool
Databases, Factual
Infant, Newborn
Intensive Care Units, Pediatric
Patient Discharge
Predictive Value of Tests
Respiration, Artificial
Retrospective Studies