Medical College of Wisconsin
CTSICores SearchResearch InformaticsREDCap

The Impact of Obesity on Postoperative Outcomes in Adults with Congenital Heart Disease Undergoing Pulmonary Valve Replacement. Congenit Heart Dis 2015 Sep-Oct;10(5):E197-202

Date

04/29/2015

Pubmed ID

25916657

DOI

10.1111/chd.12266

Scopus ID

2-s2.0-84943659746   10 Citations

Abstract

OBJECTIVE: The impact of obesity on surgical morbidity in adults with congenital heart disease is currently unknown. The aim of our study was to investigate the impact of obesity on postoperative outcomes in adults with congenital heart disease undergoing reoperation for pulmonary valve replacement.

METHODS: A retrospective analysis was performed assessing the influence of obesity on surgical outcomes. Obesity was defined as a body mass index ≥30 kg/m2.

RESULTS: The mean body mass index of the cohort was 25.9 ± 6.9 kg/m2 . The cohort included 71 patients with 17 patients (24%) being obese. There was no postoperative mortality. Obese patients had a longer hospital length of stay (6.6 vs. 4.7 days; P < .001) and increased incidence of postoperative arrhythmias (29% vs. 5.6%; P = .003) compared with nonobese patients. Multivariable analysis performed using logistic regression with backwards elimination demonstrated obesity was independently associated with hospital length of stay >5 days (odds ratio [OR] = 5.2; 95% confidence interval [CI]: 1.5-18.2, P = .01) and with increased postoperative arrhythmias (OR = 4.2; 95% CI: 1.7-40, P < .01).

CONCLUSIONS: Obesity is associated with increased morbidity in adults with congenital heart disease undergoing pulmonary valve replacement, including longer hospitalization and higher risk for postoperative arrhythmias.

Author List

Buelow MW, Earing MG, Hill GD, Cohen SB, Bartz PJ, Tweddell JS, Ginde S

Authors

Peter J. Bartz MD Professor in the Pediatrics department at Medical College of Wisconsin
Matthew W. Buelow MD Assistant Professor in the Pediatrics department at Medical College of Wisconsin
Scott B. Cohen MD Associate Professor in the Medicine department at Medical College of Wisconsin
Salil Ginde MD, MPH Associate Professor in the Pediatrics department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adolescent
Adult
Arrhythmias, Cardiac
Body Mass Index
Female
Heart Defects, Congenital
Heart Valve Prosthesis Implantation
Humans
Length of Stay
Logistic Models
Male
Middle Aged
Multivariate Analysis
Obesity
Odds Ratio
Pulmonary Valve
Reoperation
Retrospective Studies
Risk Assessment
Risk Factors
Time Factors
Treatment Outcome
Wisconsin
Young Adult
jenkins-FCD Prod-482 91ad8a360b6da540234915ea01ff80e38bfdb40a