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Bone remodelling after growth factor and cyclosporine A therapy for aplastic anemia. J Rheumatol 1991 May;18(5):738-42

Date

05/01/1991

Pubmed ID

1865422

Scopus ID

2-s2.0-0025899228 (requires institutional sign-in at Scopus site)   4 Citations

Abstract

We describe a patient with viral induced aplastic anemia who developed severe bone pain after treatment with multiple courses of antithymocyte globulin, cyclosporine A, recombinant human granulocyte macrophage colony stimulating factor and deferoxamine. Radiographs and bone biopsy revealed extensive new trabecular bone formation in long bone diaphyses and adjacent periosteal reaction. The effects of hematopoietic growth factors, cyclosporine A and deferoxamine on bone metabolism are reviewed.

Author List

Derfus BA, Csuka ME, Carrera GF, Hanson GA, Smith RE

Authors

Guillermo F. Carrera MD Adjunct Professor in the Radiology department at Medical College of Wisconsin
Mary Ellen Csuka MD Professor in the Medicine department at Medical College of Wisconsin




MESH terms used to index this publication - Major topics in bold

Adolescent
Anemia, Aplastic
Antilymphocyte Serum
Bone and Bones
Cyclosporins
Deferoxamine
Female
Fibula
Granulocyte-Macrophage Colony-Stimulating Factor
Growth Substances
Humans
Radiography
Recombinant Proteins
Tibia