Large granular lymphocytic leukemia presenting late after solid organ transplantation: a case series of four patients and review of the literature. Transplant Proc 2014 Dec;46(10):3278-81
Date
09/23/2014Pubmed ID
25240311DOI
10.1016/j.transproceed.2014.05.083Scopus ID
2-s2.0-84926339267 (requires institutional sign-in at Scopus site) 6 CitationsAbstract
Post-transplantation lymphoproliferative disorder (PTLD) is a significant complication of solid organ transplantation. Most PTLD is of the B-cell subtype, although T-cell subtype PTLD uncommonly occurs. T-cell PTLDs are usually aggressive neoplasms and shorten patient and allograft survivals significantly. We present a single-center case series of 4 patients who developed T-cell large granular lymphocytic (LGL) leukemia, a rare T-cell PTLD characterized by large granular lymphocytes that have characteristic azurophilic granules and a highly variable clinical course.
Author List
Kataria A, Cohen E, Saad E, Atallah E, Bresnahan BAuthors
Ehab L. Atallah MD Professor in the Medicine department at Medical College of WisconsinEhab R. Saad MD Director, Professor in the Medicine department at Medical College of Wisconsin
MESH terms used to index this publication - Major topics in bold
AgedFemale
Humans
Leukemia, Lymphoid
Male
Middle Aged
Organ Transplantation
