Myasthenia gravis associated with etanercept therapy. Muscle Nerve 2009 Jun;39(6):866-70
Date
04/18/2009Pubmed ID
19373885DOI
10.1002/mus.21280Scopus ID
2-s2.0-67049145696 (requires institutional sign-in at Scopus site) 52 CitationsAbstract
Etanercept is an antagonist of tumor necrosis factor alpha that was developed to treat rheumatoid arthritis. In this report we present a patient who developed myasthenia gravis while taking etanercept and had resolution of symptoms after stopping it. This is the first report of this potential side effect and is of additional interest, because etanercept has been proposed as a treatment for myasthenia gravis.
Author List
Fee DB, Kasarskis EJAuthor
Dominic B. Fee MD Vice Chair, Professor in the Neurology department at Medical College of WisconsinMESH terms used to index this publication - Major topics in bold
AgedAntirheumatic Agents
Arthritis, Rheumatoid
Autoantibodies
Deglutition Disorders
Etanercept
Humans
Immunoglobulin G
Male
Muscle, Skeletal
Myasthenia Gravis
Neuromuscular Junction
Pharynx
Receptor Protein-Tyrosine Kinases
Receptors, Cholinergic
Receptors, Tumor Necrosis Factor
Tumor Necrosis Factor-alpha